Bevacizumab-related Remote Intracranial Hemorrhages After Glioma Resection: A Cautionary Note Regarding the “Safe” Cessation Period

We present a patient with multifocal intracerebral hemorrhages after surgery for recurrent glioblastoma multiforme. His course of BV was temporarily ceased 6 weeks before repeat surgery. Our experience indicates that the anti-VEGF actions of BV can persist for longer than 6 weeks, with the potential consequence of hemorrhagic CNS complications.
Source: Neurosurgery Quarterly - Category: Neurosurgery Tags: Case Report Source Type: research