Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice

Cannabis accounts for over 75% of all federally illicit drug use in the United States alone (Ramesh and Haney, 2015). As legal restrictions ease and access to cannabis increases, many view cannabis as a low-risk recreational alternative to other drugs (Hall and Kozlowski, 2017). Regardless, 2-6% of cannabis users in the United States will develop some level of dependence (Hasin et al., 2016), as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as Cannabis Use Disorder (CUD).

Source: Drug and Alcohol Dependence - July 7, 2018 Category: Addiction Authors: Kristen R. Trexler, Sara R. Nass, Molly S. Crowe, Joshua D. Gross, Margaret S. Jones, Austin W. McKitrick, David P. Siderovski, Steven G. Kinsey Tags: Full length article Source Type: research