Evaluation of the potential role of inherited and acquired thrombophilia in unexplained infertility

We examined 70 women with UI and compared them with a control group of 70 women who had conceived spontaneously with at least one uneventful pregnancy and no history of miscarriage during the period from November 2011 to March 2013. All women were tested for the presence of inherited [factor V Leiden (FVL) mutation and deficiencies in proteins S and C and antithrombin III (ATIII)] or acquired (lupus anticoagulant and anticardiolipin antibodies) thrombophilic factors. ResultsAt least one inherited or acquired thrombophilic factor was detected in 42.86% (30/70) of women with UI compared with 8.57% (6/70) in the control group (P
Source: Journal of Evidence-Based Women’s Health Journal Society - Category: OBGYN Tags: Original articles Source Type: research