A pilot investigation of differential neuroendocrine associations with fronto-limbic activation during semantically-cued list learning in mood disorders

Mood disorders (MD), such as major depressive disorder (MDD) and bipolar disorder (BD) are characterized by objective impairments in episodic memory of moderate effect sizes; these include tests of verbal list learning, recall, and working memory (Ahern and Semkovska, 2017; Langenecker et  al., 2010). The neural basis for learning and memory decrements may relate to significant overlap between brain regions recruited for encoding and retrieval and the neural alterations characteristic of depression (Okon-Singer et al., 2015).

Source: Journal of Affective Disorders - July 7, 2018 Category: Neurology Authors: A.T. Peters, R.A. Smith, M.T. Kassel, M. Hagan, P. Maki, A. Van Meter, E.M. Brice ño, K.A. Ryan, A.L. Weldon, S.L. Weisenbach, M.N. Starkman, S.A. Langenecker Source Type: research