Differential expression of Leukemia inhibitory factor and insulin like growth factor-1 between normal pregnancies, partial hydatidiform moles and complete hydatidiform moles

Leukemia inhibitory factor (LIF) and insulin like growth factor-1 (IGF-1) are two of the most important growth factors mediating trophoblast actions. We hypothesized that the localization and expression patterns of LIF and IGF-1 in partial and complete hydatidiform moles (HM) compared with normal first trimester placentas may provide an understanding of the proliferative processes in HMs.

Source: Placenta - July 6, 2018 Category: Reproduction Medicine Authors: Ozge Senem Yucel cicek, Emine Rumeysa Hekimoglu, Mert Turgal, Pergin Atilla, Ayse Nur Cakar, Alp Usubutun, Mehmet Sinan Beksac Source Type: research