A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia

We describe a case of CEL-NOS with two hierarchically related non-specific cytogenetic rearrangements, associated with an NPM1 mutation and followed by evolution to secondary AML. NPM1 mutations are not previously described in CEL-NOS.
Source: Leukemia Research Reports - Category: Hematology Source Type: research