Tunable and sustained-release characteristics of venlafaxine hydrochloride from chitosan–carbomer matrix tablets based on in situ formed polyelectrolyte complex film coating

In conclusion, CS–CBM matrix tablets are promising system to tune and control the release of highly water-soluble drugs with good system robustness.Graphical AbstractChitosan–carbomer matrix system is beneficial to tune and control drug release with good system robustness. The in vitro release method can be used as a tool for in vivo bioavailability predication, with level A in vitro and in vivo correlation (IVIVC) established successfully.
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research