Partial loss of ATP13A2 causes selective gliosis independent of robust lipofuscinosis

This study suggests that heterozygous loss-of-function mutations in ATP13A2 are likely harmful and indicates that glial involvement in the disease process may be an early event that positions the CNS for subsequent disease development.

Source: Molecular and Cellular Neuroscience - July 5, 2018 Category: Neuroscience Source Type: research