Mapping anisotropy improves QCT-based finite element estimation of hip strength in pooled stance and side-fall load configurations

Hip fractures lead to mortality, morbidity and high health care costs. The effective prevention of hip fractures requires an accurate diagnosis of osteoporosis, which is currently based on measurement of areal bone mineral density (aBMD) measured by dual energy x-ray absorptiometry (DXA). However, the majority of fractures occur in patients with aBMD above the diagnostic threshold [1 –3]. This reflects the fact that aBMD alone has high specificity but low sensitivity. Alternatively, Kopperdahl et al.
Source: Medical Engineering and Physics - Category: Biomedical Engineering Authors: Source Type: research