Nicotine metabolite ratio predicts smoking topography: The Pennsylvania Adult Smoking Study

Cigarette smokers regulate their nicotine dose or intake by the number of cigarettes smoked daily and the amount of smoke inhaled. Puffing behaviors, or smoking topography, is associated with measures of smoke exposure such as expired carbon dioxide, nicotine intake, and cotinine (Blank et al., 2009; Hammond et al., 2005; Lee et al., 2003; Ross et al., 2016b; Strasser et al., 2005), and much of the relationship between cigarettes per day (CPD) and nicotine intake is mediated through puff volume (Krebs et al., 2016).
Source: Drug and Alcohol Dependence - Category: Addiction Authors: Tags: Full length article Source Type: research