Predicting the presence of high-risk oesophageal varices using noninvasive parameters in Egyptian cirrhotic patients

BackgroundPortal hypertension commonly accompanies liver cirrhosis. Bleeding because of oesophageal varices (OV) is one of the most dreaded complications of cirrhosis because of its high mortality rate. Endoscopy is recommended for the screening of OV. Aim of the workWe aimed to assess the value of a model for end-stage liver disease (MELD) and MELD-Na scores, platelet count, alanine aminotransferase, aspartate aminotransferase and spleen size as predictors of OV. Patients and methodsA total of 100 patients with established liver cirrhosis (80 men, 20 women) were enrolled in the study. All patients were subjected to a full clinical assessment and routine laboratory investigations. Child–Turcotte–Pugh, MELD and MELD-Na scores were calculated for each patient. Upper gastrointestinal endoscopy was performed for all patients. ResultsThe means of both MELD and MELD-Na were significantly higher among patients with OV. MELD at least 11.5 and MELD-Na at least 14.5 were both sensitive and specific for the presence of OV. Also, the MELD score showed increasing values with increasing grades of OV (P
Source: Egyptian Liver Journal - Category: Gastroenterology Tags: Original articles Source Type: research