A Cortical Shape-Adaptive Approach to Local Gyrification Index

Cortical gyrification is a dynamic process involving cortical expansion, sharpening of gyri and deepening of sulci in early brain development, followed by flattening and opening of sulci and narrowing of gyral crowns with aging (Zilles et  al., 1988; 1989; Armstrong et al., 1995). The process of gyrification is often studied from a maturational perspective by tracing global or local developmental trajectories over time. Additionally, it has been shown that local cortical gyrification is related to brain development (Zilles et al., 1988; Armstrong et al., 1995; Luders et al., 2004; Lui et al., 2011; Li et al., 2014b; Kim et al., 2016) and pathological disorders (Schmitt et al., 2002; Harris et al., 2004; Gaser et al., 2006; Schaer et al., 2008; Lebed et al., 2013).

Source: Medical Image Analysis - July 2, 2018 Category: Radiology Authors: Ilwoo Lyu, Sun Hyung Kim, Jessica B. Girault, John H. Gilmore, Martin A. Styner Source Type: research