Higher sympathetic activity as a risk factor for skeletal deterioration in pheochromocytoma
Despite the potential biological importance of sympathetic activity in human bone metabolism, its effects on bone microarchitecture, a key determinant of bone quality, has not been thoroughly studied. In the present study, we investigated the lumbar spine trabecular bone score (TBS) as an indicator of skeletal deterioration in pheochromocytoma. Among 620 consecutive patients with newly diagnosed adrenal incidentaloma, 29 with histologically confirmed pheochromocytoma (a catecholamine-secreting neuroendocrine tumor) and 266 with nonfunctional adrenal incidentaloma were defined as cases and controls, respectively.
Source: Bone - Category: Orthopaedics Authors: Beom-Jun Kim, Mi Kyung Kwak, Jae Seung Kim, Seung Hun Lee, Jung-Min Koh Tags: Full Length Article Source Type: research
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