High prevalence of multidrug-resistant international clones among macrolide-resistant Streptococcus pneumoniae isolates in immunocompromised patients in Tunisia

Streptococcus pneumoniae is one of the major pathogens responsible for meningitis as well as respiratory tract infections such as otitis and pneumonia. The prevalence of β-lactam resistance and the role of atypical pathogens in community-acquired respiratory tract infections has led to an increase in macrolide prescription. However, macrolide-resistant isolates have increased considerably in the last decade, with important geographical variations in involved phenot ypes and genotypes. This increase is due to antibiotic consumption and/or clonal diffusion of resistant strains [1].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research