Predictors of outcome in patients with severe sepsis or septic shock due to extended-spectrum β-lactamase-producing Enterobacteriaceae

Bloodstream infections (BSI) caused by extended-spectrum β-lactamases (ESBL)-producing Enterobacteriaceae (E) are associated with high rates of treatment failure and increased mortality, especially when appropriate antimicrobial therapy is delayed [1-5]. On this basis, the choice of an early effective empirical antibiotic therapy in critically ill patien ts with sepsis and/or septic shock is crucial to reduce the high rates of complications and unfavourable outcome [5].

Source: International Journal of Antimicrobial Agents - July 2, 2018 Category: Drugs & Pharmacology Authors: A. Russo, M. Falcone, B. Guti érrez-Gutiérrez, E. Calbo, B. Almirante, P.L. Viale, A. Oliver, P. Ruiz-Garbajosa, O. Gasch, M. Gozalo, J. Pitout, M. Akova, C. Peña, J.M. Cisneros, A. Hernández-Torres, A. Farcomeni, N. Prim, J. Origüen, G. Bou, E. Tacc Source Type: research