Silica nanoparticles embedded with water insoluble phthalocyanines for the photoinactivation of microorganisms

Antimicrobial resistance is a growing problem that complicates the treatment of infections acquired in the hospitals and in the community [1]. Therefore it is important to search for alternative therapeutic modalities [2]. Some modifications to the application of photodynamic therapy (PDT) for the treatment of cancer have been proposed for photokilling of microorganisms [3]. This approach, called photodynamic inactivation (PDI), is based on the preferential accumulation of the photosensitizer in the microbial cells.

Source: Photodiagnosis and Photodynamic Therapy - July 2, 2018 Category: Laser Surgery Authors: Estefania Baigorria, Eugenia Reynoso, M. Gabriela Alvarez, M. Elisa Milanesio, Edgardo N. Durantini Source Type: research