Melatonin attenuates postovulatory oocyte dysfunction by regulating SIRT1 expression

In conclusion, our data strongly indicate that melatonin delays postovulatory mouse oocyte aging via a SIRT1–MnSOD-dependent pathway, which may provide a molecular mechanism support for the further application of melatonin in the assisted reproductive technology field.

Source: Reproduction - July 2, 2018 Category: Reproduction Medicine Authors: Yang, Q., Dai, S., Luo, X., Zhu, J., Li, F., Liu, J., Yao, G., Sun, Y. Tags: Research Source Type: research