Reticular Pseudodrusen and Thin Choroid Are Associated With Angioid Streaks

Pseudoxanthoma elasticum (PXE) is genetic disorder affecting multiple organs including skin, eyes, and cardiovascular system. It is an autosomal recessive disorder caused by mutations in ABCA6 gene1 and is characterized by fragmentation and mineralization of elastin fibers that affects the connective tissues. The reported incidence of PXE varies from one in 25,000 to one in 100,000.2Characteristic ophthalmic features of PXE include angioid streaks, peau d'orange, optic disc drusen, and comet lesions.3,4 Angioid streaks are irregular disruptions in the Bruch's membrane that are frequently

Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - June 21, 2018 Category: Opthalmology Authors: Vinod Kumar, MS, DNB, MNAMS, FRCS (Glasg) Source Type: research