Wnt-Spectrum Vitreoretinopathy Masquerading as Congenital Toxoplasmosis

Wnt-spectrum vitreoretinopathies are a group of rare genetic disorders, including familial exudative vitreoretinopathy (FEVR) and Norrie disease, of retinal angiogenesis where the peripheral retina fails to vascularize resulting in ischemia and neovascularization.1,2 The majority of patients exhibit severe visual impairment as a consequence of progressive complications, including cataracts, macular dragging, retinal detachment, and amblyopia.3 –6FEVR/Norrie was classically described as an autosomal dominant condition,7 but cases have been reported with nearly all modes of inheritance.8

Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - June 21, 2018 Category: Opthalmology Authors: Natalia F. Callaway, MD, MS Source Type: research