Serial Swept-Source Optical Coherence Tomography Features of Gentamicin Macular Toxicity: A Glimpse Into the Injury Cascade

Gentamicin (Gentak; Akorn, Lake Forest, IL) toxicity manifests as a vaso-occlusive event with nonperfusion areas demarcating the macular infarction. The postulated etiology is a vascular or receptor-mediated process.1 The availability of optical coherence tomography (OCT) has improved understanding of this macular insult, but few published cases report use this diagnostic tool.2,3 The current case adds to literature by using swept-source OCT (SS-OCT) to image early gentamicin toxicity within 12 hours of subconjunctival injection. By reporting outer retinal damage to be the initial event, in
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - Category: Opthalmology Authors: Source Type: research