Assessment of Differences in Retinal Microvasculature Using OCT Angiography in Alzheimer's Disease: A Twin Discordance Report

Alzheimer's disease (AD), the most common cause of dementia, is defined by both neuropathology and clinical symptoms. The neuropathology of AD consists of two hallmark elements: the deposition of plaques (amyloid) and tangles (tau protein). It is likely that these two biochemical conditions lead to the destruction or death of nerve cells and subsequently cause the clinical symptoms, suggesting that both amyloid and tau can be assessed as early AD markers.1 However, measuring amyloid and tau through cerebrospinal fluid is not easily attainable for clinical diagnosis, and both may not be

Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - June 21, 2018 Category: Opthalmology Authors: Dilraj S. Grewal, MD Source Type: research