Hippocampal volume and vasculature before and after exercise in treatment-resistant schizophrenia

Schizophrenia is associated with poor cognitive function and elevated cardiometabolic disease risk. These health concerns may exacerbate neurocognitive dysfunction associated with hippocampal abnormalities, particularly hippocampal volume reductions. Regular exercise is thought to improve symptom severity, reduce depression, and improve cognition in schizophrenia, and may trigger exercise-mediated hippocampal growth. The potential for the benefits of exercise for treatment-resistant schizophrenia patients has not been clearly assessed.

Source: Schizophrenia Research - June 28, 2018 Category: Psychiatry Authors: M.L. Woodward, K.M. Gicas, D.E. Warburton, R.F. White, A. Rauscher, O. Leonova, W. Su, G.N. Smith, A.E. Thornton, A.T. Vertinsky, A.A. Phillips, V.M. Goghari, W.G. Honer, D.J. Lang Source Type: research