Decreased use of active coping styles contributes to elevated allostatic load index in first-episode psychosis

Stressful life events play an important role in the development, course and outcome of psychotic disorders. It has been shown that a history of childhood and adult life adversities accounts for about threefold increase of psychosis risk (Beards et al., 2013; Varese et al., 2012). A history of childhood trauma has been also related to early non-response to antipsychotic treatment, more severe psychotic symptoms and poor long-term outcomes in this group of patients (Misiak et al., 2017a,b, Misiak et al., 2016; Misiak and Frydecka, 2016; Mondelli et al., 2015).

Source: Psychoneuroendocrinology - June 27, 2018 Category: Psychiatry Authors: B łażej Misiak, Kamila Kotowicz, Olga Loska, Filip Stramecki, Jan Aleksander Beszłej, Jerzy Samochowiec, Marcin Jabłoński, Piotr Podwalski, Katarzyna Waszczuk, Michał Wroński, Anna Michalczyk, Leszek Sagan, Patryk Piotrowski Source Type: research