Extraction and isolation of cannabinoids from marijuana seizures and characterization by 1H NMR allied to chemometric tools

Marijuana, a drug derived from the Cannabis sativa L. plant, is the world's most consumed illicit drug. In this paper, a total of 156 marijuana samples seized in the state of Esp írito Santo (ES), Brazil were studied and analysed by proton nuclear magnetic resonance (1H NMR) spectroscopy to identify the major cannabinoids present. A crude extract of all samples was purified using high performance liquid chromatography so that these compounds could serve as reference substan ces. Nine fractions were obtained and analysed by 1H NMR and gas chromatography–mass spectrometry (GC–MS), with five presented cannabinoids.

Source: Science and Justice - June 27, 2018 Category: Forensic Medicine Authors: J úlia de A. Leite, Marcos V.L. de Oliveira, Raphael Conti, Warley de S. Borges, Thalles R. Rosa, Paulo R. Filgueiras, Valdemar Lacerda, Wanderson Romão, Álvaro C. Neto Source Type: research