Changes in sexual hormones, serotonin, and cortisol concentrations following oral administration of melatonin in castrated and intact dogs

Melatonin is a regulatory hormone that orchestrates many responsesto changes occurring in the body and environment. In the present study, melatonin was administrated immediately after time of castration to 20 male dogs (3mg/10 Kg, PO, four groups (n=5): melatonin, castrated, castrated+melatonin, control) for 30 days. Blood samples were collected weekly from jugular vein from 2 days after melatonin administration. Steroidal hormones (estradiol, testosterone, progesterone, cortisol) and serotonin were measured by ELISA Kits.
Source: Journal of Veterinary Behavior: Clinical Applications and Research - Category: Veterinary Research Authors: Source Type: research