Slice-level diffusion encoding for motion and distortion correction

Diffusion MRI (dMRI) offers a unique observation window into tissue microstructure in-vivo Le Bihan et  al. (1986). Increasingly advanced biophysical modelling techniques for dMRI allow insight into microscopic tissue properties, such as axon diameter Assaf et al. (2008); Alexander et al. (2010), neurite morphology Zhang et al. (2012), global connectivity patterns Tournier et al. (2012); Wedeen et al. (2008); Steven et al. (2014) and cell size and density Panagiotaki et al. (2015). These techniques demand a rich dMRI acquisition for accurate parameter estimation, namely a high number of samples varying in direction, described by the unit vector b-vector and strength, expressed in b-valu e in the diffusion encoding space.

Source: Medical Image Analysis - June 25, 2018 Category: Radiology Authors: Jana Hutter, Daan Christiaens, Torben Schneider, Lucilio Cordero-Grande, Paddy J Slator, Maria Deprez, Anthony N Price, Donald Tournier, Mary Rutherford, Joseph V Hajnal Source Type: research