Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: sex- and time-dependent effects

Children and adults prenatally exposed to alcohol show higher rates of mental health problems than unexposed individuals, with depression and anxiety being among the more commonly encountered disorders (Famy et al., 1998; O ’Connor and Paley, 2009; Pei et al., 2011). Previous studies in rats showed that prenatal alcohol exposure (PAE) can indeed increase depressive- and anxiety-like behavior in adulthood (Brocardo et al., 2012; Cullen et al., 2013; Hofmann et al., 2005; Varlinskaya and Mooney, 2014; Wilcoxon et al., 2005).
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research