NF2 and ATRX gene copy number losses on a case of ovarian ependymoma

We describe a 27year old female who presented to the emergency room with a 3week history of cough and shortness of breath. Further workup disclosed a left pelvic mass and extensive intra-abdominal metastases. Pathology revealed sheets of monomorphic cells within a fibrillary stroma, papillary projections, true ependymal rosettes, and pseudorosettes consistent with an ependymoma of ovarian origin.

Source: Human Pathology - June 23, 2018 Category: Pathology Authors: Liurka V. Lopez, Siddharth Bhattacharyya, Eric D. Carlsen, David Bartlett, Uma N.M. Rao Tags: Case Study Source Type: research