Identification of CFE-2, a New Plasmid-Encoded AmpC β-Lactamase from a Clinical Isolate of Citrobacter freundii

Citrobacter species are Gram-negative, straight and facultative anaerobic bacilli. Many members of the Citrobacter sp. are naturally resistant to amoxicillin and early generation cephalosporins. Previous studies have proposed C. freundii is more resistant to many antimicrobial agents than other members of the Citrobacter sp. [1, 2]. Furthermore, isolates of C. freundii in recent years have demonstrated resistance not only to traditional agents such as ampicillin, carbenicillin, and cephalothin, but also to newer β-lactam agents such as third-generation cephalosporins, monobactams; and some C.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Short Communication Source Type: research