What Is the Effect of Anti-GnRH Immunization on Plasmatic Levels of Anti Mullerian Hormone?

Thanks to a wide “off – license”, the use of the anti-GnRH vaccine Improvac®, initially dedicated to the boar immune castration, is possible in stallions as a potentially reversible alternative to surgical castration. First immunization in stallions results in an inhibition of sexual steroids secretion and sp ermatogenesis, with a reversible effect in more than 90% of the cases [2, 4, 5, 9]. Anti-Mullerian hormone (AMH) is produced by embryonic Sertoli cells in the male and is strongly expressed in fetal, neonatal and prepuberal testis.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research