Age-related Preferential Effects of Mitochondrial Oxidative Function on Progressive Motility and Decline of Mitochondrial Respiratory Capacity in Stallion Spermatozoa

The objective of this study was to evaluate the relationship between stallion age, sperm quality, and mitochondrial function for age-related patterns of dysfunction in fresh stallion semen. This was accomplished by employing an array of mitochondrial oxidative phosphorylation inhibitors and uncouplers of mitochondrial oxygen consumption (MITOX) in fresh semen from Quarter Horse stallions (n=55) ranging in age from 4 to 25 years with a mean age of 12.2+/-4.7 (mean+/-SD).
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research