Significant Correlation Between the proAKAP4 Concentration and the Total and Progressive Motility in Stallion Sperm After Thawing

A-kinase anchor protein 4 (AKAP4) is playing a central role in flagellar structure, chemotaxis, capacitation and sperm motility. In mammals, AKAP4 is expressed during spermatogenesis. AKAP4 is synthesized as a precursor, proAKAP4, which is cleaved into mature AKAP4 during fibrous sheath assembly (Luconi et al., Front Biosci. 2011; 16:1315-1330). The proAKAP4 is a good indicator of sperm quality in humans and also in boars (Sergeant et al., Anim Reprod Sci. 2016; 169: 125-126; Teijeiro and Marini, Reproduction 2012; 143: 773-785).
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research