Preimplantation Genetic Diagnosis in Donkey Embryos After Biopsy

New knowledge on mammalian genomes allows embryo selection for specific characteristics before transfer, termed preimplantation genetic diagnosis (PGD). PGD also allows elimination of disease due to inherited genetic mutations, and facilitates crossbreeding and cryobanking of interesting genetic characteristics. To perform PGD, a few embryonic cells are required, followed by whole genome amplification (WGA). This technique is widely used in man. In horses, PGD has been performed successfully prior to embryo cryopreservation (Choi et.al.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research