Evaluation of Equine Endometrium during Maternal Recognition of Pregnancy Utilizing RNA Sequencing

Equine maternal recognition of pregnancy (MRP) is a process whose signal remains unknown. During MRP the conceptus and endometrium communicate to attenuate prostaglandin F2 α (PGF) secretion thus sparing the corpus luteum and maintaining progesterone production. Recognition of a mobile and viable conceptus by the endometrium is critical prior to days 14-16 post-ovulation (PO). Between days 14-16 PO in the non-pregnant mare, endometrium produces PGF, which initiates lu teolysis. Previous gene expression analyses have failed to robustly reveal possible candidates involved in MRP.

Source: Journal of Equine Veterinary Science - June 23, 2018 Category: Veterinary Research Authors: K.M. Klohonatz, A.D. Islas-Trejo, J.F. Medrano, A.M. Hess, S.J. Coleman, M.G. Thomas, G.J. Bouma, J.E. Bruemmer Source Type: research