Reciprocal Paternal and Maternal Control of Angiogenesis in Equine Chorioallantois

The retrotransposon Gag-like 1 (Rtl1) gene is pivotal in the development of the mouse chorioallantois (CA). Rtl1 and one of its repressor microRNA, miR-127 (located in Rtl1_antisense [Rtl1_as]), are located in an imprinted domain. Rtl1/Rtl1_as are involved in angiogenesis and maintenance of fetal capillaries during development of the placenta (Kitazawa et al. Genes to Cells. 2017;22:174-188). Currently, there is no information available about the presence or kinetics of Rtl1/Rtl1_as in equine CA during pregnancy.

Source: Journal of Equine Veterinary Science - June 23, 2018 Category: Veterinary Research Authors: P. Dini, A. Esteller-Vico, S.C. Loux, M. Carossino, K.E. Scoggin, T.S. Kalbfleisch, P. Daels, B.A. Ball Source Type: research