Peripheral Markers Profiles in Response to Treatment for Experimental Placentitis in Mares

This study aimed to describe the plasma concentrations of estradiol-17 β, progesterone, alpha-fetoprotein (AFP), and serum amyloid A (SAA) in response to treatment for placentitis. Eighteen pony mares carrying normal pregnancies 270-295d gestation were enrolled in the study for two foaling seasons. Experiment I, mares were randomly assigned to one of three groups: INF ECT (n=6; experimental induction of placentitis, no treatment); FIRO (n=6; experimental induction of placentitis and treatment with firocoxib 0.3 mg/kg for 24h and then maintained with 0.1 mg/kg until delivery, with onset of administration beginning 3 days before induction of placentitis) and NORM ( n=6; normal foaling no infection).
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research