Expression of Oestrogen Receptor α Is Negatively Correlated With Collagen Density in the Mare’s Cervix

Failure of cervical dilation during oestrus is a recognised predisposing factor for post-breeding endometritis. As a prerequisite step to understanding the mechanisms behind such failure, this study aimed to elucidate normal expression of cervical hormone receptors and collagen modelling at different stages of the oestrous cycle. We tested the two hypotheses that: (1) the proportion of collagen staining and (2) the expression of steroid receptors in mares ’ cervices differ with stage of the oestrous cycle, and site within the cervix.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research