Concentrations of Gentamicin In Serum, Intrauterine Fluid, and Endometrial Tissue After Intravenous Administration in Healthy Mares

Endometritis in mares remains an important clinical condition for the equine breeding industry. The treatment of choice is antimicrobial therapy, commonly administered into the uterus. Disadvantages of the intrauterine (i.u.) route, however, include the risk of contamination, dependence on estrous cycle stage and inhomogeneous distribution within the endometrium. Therefore, the objective of the present study was to assess gentamicin concentrations in serum, i.u. fluid (IUF), and endometrial tissue (ET) of non-pregnant healthy mares after intravenous (i.v.) gentamicin administration.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research