Electroencephalographic biomarkers as predictors of methylphenidate response in attention-deficit/hyperactivity disorder

This study aimed to replicate and extend previous EEG biomarkers. The international Study to Predict Optimized Treatment for ADHD (iSPOT-A), a multi-center, international, prospective open-label trial, enrolled 336 children and adolescents with ADHD (11.9 yrs; 245 males; prescribed methylphenidate) and 158 healthy children. Treatment response was established after six weeks using the clinician rated ADHD-Rating Scale-IV.

Source: European Neuropsychopharmacology - June 22, 2018 Category: Psychiatry & Psychology Authors: Martijn Arns, Madelon A. Vollebregt, Donna Palmer, Chris Spooner, Evian Gordon, Michael Kohn, Simon Clarke, Glen R. Elliott, Jan K. Buitelaar Source Type: research