Utility of STAT 6 and 13q14 deletion in the classification of the benign spindle cell stromal tumors of the breast

The boundaries of the benign spindle cell stromal tumors of the breast are still confusing. This is the reason why different names are interchangeably used for the same tumor and vice versa the same name for different tumors. Therefore we studied the immunoexpression of easily available markers, such as CD34, alpha-smooth muscle actin, desmin, with the addition of STAT6, as well as the chromosome 13q14 region by fluorescence in situ hybridization analysis in a series of 19 cases of benign spindle cell stromal tumors of the breast.

Source: Human Pathology - June 22, 2018 Category: Pathology Authors: Gaetano Magro, Giuseppe Angelico, Alberto Righi, Stefania Bonini, Lucia Salvatorelli, Juan Palazzo Tags: Original Contributions Source Type: research