Increased plasma Interleukin-1 β level is associated with memory deficits in type 2 diabetic patients with mild cognitive impairment

The prevalence of chronic complications in type 2 diabetes mellitus (T2DM) has increased significantly over the past decades and poses a significant threat to the health. Several researches have reported that T2DM patients exhibit an increased risk of mild cognitive impairment (MCI), particularly memory impairment (Cheng et al., 2012; Gorska-Ciebiada et al., 2014; van Bussel et al., 2015). MCI, a transitional stage between normal cognition and Alzheimer disease (AD) (Mariani et al., 2007), has caused concern because of the high conversion from MCI to AD at a rate of 10% to 15% per year (Janoutova et al., 2015).

Source: Psychoneuroendocrinology - June 22, 2018 Category: Psychiatry Authors: Sai Tian, Rong Huang, Jing Han, Rongrong Cai, Dan Guo, Hongyan Lin, Jiaqi Wang, Shaohua Wang Source Type: research