A fully automated system using transcription-mediated amplification for the molecular diagnosis of hepatitis E virus in human blood and faeces

The past 10 years have seen the recognition of the hepatitis E virus (HEV) as a pathogen of global significance. HEV strains that infect humans belong to 4 major genotypes and are subdivided in several subtypes [1]. Genotypes 1 and 2 infect only humans in developing countries [2]. Genotypes 3 and 4 are transmitted zoonotically in industrialized countries [2]; HEV genotype 7, which infects camels can be transmitted to humans [3]. Symptoms of HEV infection can vary from asymptomatic to fulminant hepatitis.

Source: Journal of Clinical Virology - June 22, 2018 Category: Virology Authors: Florence Abravanel, S ébastien Lhomme, Sabine Chapuy-Regaud, Jean-Michel Mansuy, Jérôme Boineau, Karine Sauné, Jacques Izopet Source Type: research