Plasma levels of leptin in patients with Pathological Gambling, Internet Gaming and Alcohol Use Disorder

Leptin, a product of the leptin gene (Campfield and Smith, 1998), is a 16kDa polypeptide and involved in appetite regulation and body energy balance (Campfield et al., 1996; Campfield et al., 1995; Kiefer et al., 2005; Pelleymounter et al., 1995). It is secreted by white adipocytes, circulates in the blood and enters the central nervous system via specific binding proteins (Campfield and Smith, 1998). It is involved in the control of satiety and body fat stores and can diminish food intake through central interaction with the hypothalamus and other brain areas (Pelleymounter et al., 1995).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research