Maternal high fat diet alters offspring epigenetic regulators, amygdala glutamatergic profile and anxiety

The “developmental origins of health and disease” (DOHaD) hypothesis posits that the maternal environment during the prenatal and perinatal period can program offspring vulnerability to a host of long-term health consequences. Maternal nutrition plays a crucial role in offspring development both in utero, and during critical periods of growth after birth; and growing evidence indicates a link between maternal obesity and offspring risk of metabolic disorders, cardiovascular disease, and neurocognitive deficits.
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research