Evaluation of a chloride-based 89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin

The remarkable stability of the 89Zr-DOTA complex has been shown in recent literature. The formation of this complex appears to require 89Zr-chloride as the complexation precursor rather than the more conventional 89Zr-oxalate. In this work we present a method for the direct isolation of 89Zr-chloride from irradiated natY foils.

Source: Nuclear Medicine and Biology - June 17, 2018 Category: Nuclear Medicine Authors: Stephen A. Graves, Christopher Kutyreff, Kendall E. Barrett, Reinier Hernandez, Paul A. Ellison, Steffen Happel, Eduardo Aluicio-Sarduy, Todd E. Barnhart, Robert J. Nickles, Jonathan W. Engle Source Type: research