Editor ’s Page

I have devoted several Editor's Pages to the SPRINT trial. In this issue of the Journal of the American Society of Hypertension, Del Pinto and colleagues1 explore the J-curve hypothesis2 using data from the SPRINT trial.3 The J-curve hypothesis is that very low achieved diastolic blood pressures are associated with increased risk for cardiovascular disease events and that this risk is particularly great in patients with pre-existing cardiovascular disease. In many ways, SPRINT is perfectly designed to test the validity –or lack thereof–of the J-curve hypothesis, given the low attained diastolic blood pressures in those randomized to intensive treatment (systolic blood pressure

Source: Journal of the American Society of Hypertension - June 17, 2018 Category: Cardiology Authors: Daniel Levy Tags: Editor's Page Source Type: research