Premorbid adjustment predictors of cognitive dysfunction in schizophrenia

Impairment or deterioration of academic and social premorbid adjustment (PA) from childhood to adolescence is a broadly recognized antecedent of schizophrenia (Allen et  al., 2001, 2005; Cannon et al., 2002; Monte et al, 2008; Reichenberg et al., 2002, 2010). It is related to the more malignant course of the illness (Galderisi et al., 2002; Rund et al., 2007; Strauss et al., 2012), thus it is considered to be a key predictor of its clinical and psychosocial outcome (Addington and Addington, 2005; Barajas et al., 2013; MacBeth and Gumley, 2008; Rund et al., 2007).

Source: Psychiatry Research - June 16, 2018 Category: Psychiatry Authors: Pentagiotissa Stefanatou, Chrysovalado-Sofia Karatosidi, Evgenia Tsompanaki, Emmanouil Kattoulas, Nicholas C Stefanis, Smyrnis Nikolaos Source Type: research