Interobserver variations in the delineation of target volumes and organs at risk and their impact on dose distribution in intensity-modulated radiation therapy for nasopharyngeal carcinoma

Intensity-modulated radiotherapy (IMRT) has better clinic outcomes in the treatment of head and neck cancer, achieving more accurate target dose distribution and better protection of normal tissues [1 –3]. However, the premise is that the planning target volumes (PTVs) and organs at risk (OARs) must be accurately delineated. The treatment plan should be designed so that the prescribed dose can accurately cover the tumor target site, whereas the dose to the OARs does not exceed the established l imit.

Source: Oral Oncology - May 2, 2018 Category: Cancer & Oncology Authors: Ying-lin Peng, Li Chen, Guan-zhu Shen, Ya-ning Li, Ji-jin Yao, Wei-wei Xiao, Lin Yang, Shu Zhou, Jia-xin Li, Wan-qin Cheng, Ying Guan, Hai-qun Xia, Shuai Liu, Chong Zhao, Xiao-wu Deng Source Type: research