The epidemiology of oral human papillomavirus infection in healthy populations: A systematic review and meta-analysis

Human papillomavirus (HPV) is the most common sexually transmitted infection in North America [1,2]. The oncogenic potential of HPV was first described in cervical cancer [3]. More recently, the link between oropharyngeal squamous cell carcinoma (OPSCC) and oral HPV infection was established [4,5]. An estimated 72% of OPSCC cases are associated with HPV in North America [6]. The incidence of OPSCC has been rising rapidly, and has overtaken cervical cancer to become the most common HPV-related cancer in the United States [6,7].

Source: Oral Oncology - May 23, 2018 Category: Cancer & Oncology Authors: Samantha Tam, Shuangshuang Fu, Li Xu, Kate J. Krause, David R. Lairson, Hongyu Miao, Erich M. Sturgis, Kristina R. Dahlstrom Tags: Review Source Type: research