Acyl-carnitine, C5DC, and C26 as potential biomarkers for diagnosis of autism spectrum disorder in children

Carnitine is an essential nutrient and the majority of carnitine is obtained from diet, mainly animal products. Carnitine exists in human body in the form of free carnitine and acyl-carnitine, and plays a vital role in energy production and fatty acid metabolism. Gut flora participate in the energy metabolism of the host and may have a profound influence on cell mitochondrial function and the development of neurodevelopmental diseases through short-chain fatty acids including propionic acid (PPA) and butyrate (BUT), produced by microbial metabolism (De Angelis et al., 2015).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research